Traditional 2D cell cultures can’t replicate the complexity of real tissues — resulting in limited insights and poor clinical ...

An interview with Lindy O’Clair, Head of Incucyte® Product Management at Sartorius 3D cell models like spheroids and ...

In fact, many modern discovery programs target a disease mechanism that simply can't be reproduced in a 2D environment, meaning the only way to achieve a useful model system is through 3D cell ...

Traditional 2D cell cultures lack the spatial complexity of real tumors. Cells grown in monolayers exhibit altered polarity, shape, and signaling, failing to replicate tumor heterogeneity and the TME.

3D cell culture models are more predictive than traditional 2D monolayer cultures, meaning that using them saves costs and time in R&D. This is beneficial as drug development is typically a high ...

In this study, a screening was carried out utilizing patient-derived 3D spheroids (tumoroids). In addition to readouts on cell viability, the Cell Painting assay was adapted for the 3D tumor model.

An international team of researchers has demonstrated a novel solvent process for pure and highly crystalline 2D perovskites, which they demonstrated in 2D/3D perovskite solar cells. A n-i-p ...