Complement molecules are the immune proteins responsible for identifying bacteria, viruses, and other foreign invaders as they circulate through our bodies. Their function helps lymphocytes to locate ...

They measured the levels of the proteins C3, C4, CH50, and C3D, which are biomarkers of the complement system.

Complement is deposited and microglia attack neurons that could otherwise recover their function. We found that B4Crry prevented microglial phagocytosis of these live neurons." ...

We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional ...

Complement is deposited and microglia attack neurons that could otherwise recover their function. We found that B4Crry prevented microglial phagocytosis of these live neurons." ...

In more recent years, it has become well established that complement also plays a role in focusing the antibody arm of the adaptive immune system on an antigen which it has tagged with a C3 split ...

Michael M. Frank, Keith Joiner, Carl Hammer, The Function of Antibody and Complement in the Lysis of Bacteria, Reviews of Infectious Diseases, Vol. 9, Supplement 5. Perspectives on Bacterial ...

Inflammation and activation of the complement system in the intracranial aneurysm (IA) wall predispose to IA rupture. We have previously shown that increased C5b-9 accumulation correlates with IA ...

References Sicard, A. et al. Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss. J. Am. Soc. Nephrol. 10.1681/ASN.2013101144 ...