The new Python was only offered in two barrel length however, 4.25" and 6", leading to customer requests for Colt to reintroduce the shorter 3" barreled model as well.

On the range with one of the new production Pythons. Since its re-introduction, Colt has added an additional variant, a 3" barreled model, to the Python series lineup in January 2022.

Colt Manufacturing Company LLC showed off the reintroduction of its .357 Magnum Python revolver at SHOT Show 2020.