The best you can do is block the content within them, such as annoying pop-ups and redirects, automatic downloads, and more. Blocking websites on your PC doesn't apply to the mobile browser.

You then type “0.0.0.0”, followed by Space, then the URL—one line for each website. Hit Control+O then Control+X to save your changes. Block websites using software ...

This is where PopUpOff, a free pop-up and overlay blocker, comes in. Let’s check it out in detail and see how you can use it to block website pop-ups on Chrome, Firefox, and Edge on your computer.