The use of linear mixed models (LMMs) in genome-wide association studies (GWAS) is now widely accepted 1 because LMMs have been shown to be capable of correcting for several forms of confounding ...

Alkes Price, Po-Ru Loh and colleagues report the BOLT-LMM method for mixed-model association. They apply their method to 9 quantitative traits in 23,294 samples and demonstrate that it provides ...