The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new ...

The prediction of protein structure is difficult for a few reasons. First, there is a huge search space — every possible 3D position for each atom in each amino acid. Second, proteins chemically ...

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to ...

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to ...

Methods such as crystallography, which we use to visualize the atoms of a protein in crystal form, failed to give us a complete picture of RPE's structure with this crucial region missing.

Hsp70 chaperone systems are very versatile machines present in nearly all living organisms and in nearly all intracellular compartments. They function in many fundamental processes through their ...

Rebecca A. Sager, Sarah J. Backe, Jennifer Heritz, Mark R. Woodford, Dimitra Bourboulia, Mehdi Mollapour, Flow cytometry FRET reveals post-translational modifications drive Protein Phosphatase-5 ...