Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported ...

Oncotarget published "Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells" which reported ...

High-resolution 3D imaging reveals enzyme activity differences and drug effects in whole organs. ... small molecules like fluorescent probes also get washed out of the tissue.

Reference: Kaczmarczyk JA, Roberts RR, Luke BT, et al. Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D ...