First simulation of a full-sized mitochondrial membrane New algorithm links different scales, bringing simulated cell a step closer Date: May 8, 2020 Source: University of Groningen Summary ...

"Simulations Unravel Outer Membrane Transport Mechanism." ScienceDaily. ScienceDaily, 6 June 2007. <www.sciencedaily.com / releases / 2007 / 06 / 070605185643.htm>.

As the gatekeepers of ion flow through cell membranes, ion channels are of key interest in numerous cellular processes. Now, a new study describes an innovative new computational model that ...

"Using complex simulations in supercomputers, we were recently able to show, together with other research groups, that the anchor causes the membrane to curve," Bhaskara says, adding that "under ...

Reference: Rizo J, Sari L, Jaczynska K, Rosenmund C, Lin MM. Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations. Proc Natl Acad Sci ...

These are then studied using detailed simulations at a molecular level. Using this technique, they successfully simulated the entire membrane of a mitochondrion, a large organelle inside cells.

The simulation also showed the luminal domain gradually unfolding, changing its conformation in ways that would open up enough space for a molecule of vitamin B12 to pass through the barrel.