A team led by Eamon Doyle, Ph.D., in the Borzage Laboratory at Children's Hospital Los Angeles developed novel computational ...

To build the model, researchers collected blood cells from young-onset ALS patients, all under age 45, and healthy male donors, whose cells were used to build a "healthy" chip, for comparison.

Blood flow regulation by acetylcholine is long established and highlighted by the 1998 Nobel Prize in Physiology or Medicine. Yet the sources of acetylcholine in human blood have been unclear.

After those early experiments, it was a long road to an FDA-approved product for humans. Niklason and her team spent more than a decade isolating blood vessel cells from human organ and tissue ...