The Arduino manages everything else on the system as well including all of the temperature sensors and fan motor control.

Adafruit TinyUSB Library for Arduino This library is a Arduino-friendly version of TinyUSB stack. It is designed with structure and APIs that are easily integrated to an Arduino Core.

Adafruit IO Arduino Library This library provides a simple device independent interface for interacting with Adafruit IO using Arduino. It allows you to switch between WiFi (ESP8266, ESP32, ESP32-S2, ...