The mission to improve the widely used simplex-method algorithm showed instead why it works so well. ... This may allow the so-called optimization experts to solve even more complex organizational ...

In this paper, a novel modified optimization algorithm is presented, which combines Nelder-Mead (NM) method with a gradient-based approach. The well-known Nelder Mead optimization technique is widely ...

Simplex optimization is one of the simplest algorithms available to train a neural network. Understanding how simplex optimization works, and how it compares to the more commonly used back-propagation ...

OXFORD, England, April 18, 2025--A new paper, released this week on bioRxiv, introduces hifiasm-ONT, a breakthrough genome assembly algorithm that enables partially phased, near telomere-to ...

New hifiasm-ONT assembly method delivers high-quality, cost-efficient near T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies across ...

George Bernard Dantzig, a Stanford University mathematics professor for three decades whose groundbreaking Simplex Algorithm has been used by industry to find the most efficient means to ...

Breakthrough algorithm enables partially phased, near telomere-to-telomere assembly using standard Oxford Nanopore Simplex reads Provided by Business Wire Apr 18, 2025, 12:15:00 PM ...