The DETMAX algorithm of Mitchell (1974a) is very commonly used for computer-generated optimal design. Although it is not the default search method for the OPTEX procedure, you can specify that it be ...

The SMC algorithm enables studies of patterns of genetic variation (for example, linkage disequilibria) and tests of hypotheses (using simulation-based approaches) that were previously intractable.

The sequential algorithm requires no initial design; in fact, it can be used to provide an initial design for the other search procedures (see the INITDESIGN= option). If you specify a data set for an ...

In this example, the algorithm screened between approximately 100,000 to 1,000,000 possible antibody sequences from the database to identify the sequence (left) that best matches the antibody ...

They employed a “structure-to-sequence” computer algorithm that can relate antibody structure determined by cryo-EM, to the DNA sequence that would produce that structure. For this, they assembled a ...

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development. The researchers, whose work appears in Science Advances on January ...