Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

References [1] Measurement of 2D density profiles using a second-harmonic, dispersion interferometer. Review of Scientific Instruments (2023).

Abstract: Objective: Detection of Atrial fibrillation (AF) from premature atrial contraction (PAC) and premature ventricular contraction (PVC) is difficult as frequent occurrences of these ectopic ...

We visualize these via multi-objective Pareto front plots and assign a weighted score to each composition that encompasses the trade-off between performance and density-based chemical uniqueness. In ...