SCOPER has simplified it significantly. Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today.

Finally, Python has another data structure, the set, which superficially resembles a dictionary. Think of it as a dictionary with only keys, but no values. Its syntax is also similar to a dictionary: ...

While recent breakthroughs such as AlphaFold3 have revolutionized protein and RNA structure prediction, they currently fail to reliably generate correct G-quadruplex structures from sequence alone.