A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk, ...

In the new study, Dr. Gan’s team engineered the Christchurch mutation into the APOE gene in mice that develop tau accumulation, and found that it protected the animals from hallmark Alzheimer ...

Mitochondrial DNA mutation accumulation may not be a determining factor in aging Date: May 29, 2025 Source: University of Tsukuba Summary: Mutations accumulated in mitochondrial DNA associated ...

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...

As a common biological sequence, DNA sequences contain important information. The discovery of frequent patterns in DNA sequences can help to study the evolution, function and variation of genes. The ...

The epigenetic clock theory suggests that aging occurs due to the accumulation of epigenetic modifications, minor changes to the chemical structure of DNA that do not alter the underlying sequence, ...

Zhongju Yuan, Tao Shen and Sheng Xu et al. AF2-mutation: adversarial sequence mutations against AlphaFold2 in protein tertiary structure prediction. Acta Materia Medica. 2024. Vol. 3 (4):462-476.

Design patterns are reusable solutions to common problems in software design. For AI and large language model (LLM) engineers, design patterns help build robust, scalable, and maintainable systems ...

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.