These proteins can have too many conformations for researchers to keep track of, says Kejia Wu, a postdoctoral researcher ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to ...

“The 3-D structure of a biomolecule determines its function. This could mean, for example, that in the future we might use folded sugars as drugs, as catalysts for chemical transformations, or as ...