Multiple subway lines have been disrupted Wednesday night after the MTA says power was lost between the Jay Street-MetroTech and Hoyt-Schermerhorn stations in Brooklyn.

A multi-vehicle crash closed part of Route 222 near Wyomissing for more than an hour Tuesday.

Sanofi should hear from the FDA in September about its filing for Sarclisa as a first-line therapy for multiple myeloma after a priority review.